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Metabolic, Incretin & Mitochondrial Research

5-Amino-1MQ Research Compound

5-Amino-1MQ (5-amino-1-methylquinolinium) is a membrane-permeable small-molecule inhibitor of nicotinamide N-methyltransferase (NNMT).

3 listed 5-Amino-1MQ presentations

Each presentation is a separate specification with its own product code. Open one to add it to your inquiry cart or to ask for a quote on WhatsApp. Pricing, availability and lot documents are confirmed for each order.

PresentationPer vialPer boxProduct code
5-Amino-1MQ 5 mg5 mg10 vials5AM
5-Amino-1MQ 10 mg10 mg10 vials10AM
5-Amino-1MQ 50 mg50 mg10 vials50AM

Amounts are per vial. mg, IU and mL describe different quantities and are not interchangeable. For laboratory research use only.

5-Amino-1MQ 5 mg, 10 vials per box — PureForm Biosciences catalog illustration

About 5-Amino-1MQ

5-Amino-1MQ is 5-amino-1-methylquinolinium, a small quinolinium compound rather than a peptide. It inhibits nicotinamide N-methyltransferase (NNMT), a cytosolic enzyme that transfers a methyl group from S-adenosylmethionine (SAM) to nicotinamide, producing 1-methylnicotinamide (1-MNA).

It comes from a structure-based series of methylquinolinium NNMT inhibitors developed at the University of Texas Medical Branch and described in 2018 as membrane-permeable and relatively selective.

Research context

Because NNMT consumes nicotinamide and SAM, inhibiting it is a way to study links between the NAD+ salvage pathway, cellular methylation potential and adipocyte metabolism. In cultured adipocytes, published work reported lower 1-MNA, higher NAD+ and SAM, and reduced lipogenesis; high-fat-diet mouse studies examined adipose tissue mass and metabolic parameters. The available data are preclinical.

What to confirm for 5-Amino-1MQ

Check these points with our team before you order:

  • The counter-ion stated on the lot documents; the quinolinium cation is supplied as a salt, for example the iodide.
  • Solubility and vehicle information for this small molecule.
  • The number of boxes you need and the US delivery destination.
  • Which lot documents you require before ordering, such as an identity or purity report.

5-Amino-1MQ: frequently asked questions

Is 5-Amino-1MQ a peptide?

No. It is a small quinolinium molecule. It is listed with peptides because it is used in related NAD+ and metabolic research.

What do the supplier names “5-amino-5mg” and “50-amino-50mg” mean?

They are abbreviations on the supplier sheet. Codes 5AM, 10AM and 50AM correspond to 5-Amino-1MQ at 5, 10 and 50 mg per vial, as on the supplier's earlier list.

Which 5-Amino-1MQ presentations are listed?

3 presentations are listed: 5 mg (5AM), 10 mg (10AM), 50 mg (50AM). Each is packed 10 vials per box, and every presentation has its own specification page and product code.

How do I request a quote for 5-Amino-1MQ?

Open the presentation you need and use Ask price to message PureForm Biosciences on WhatsApp, or add several materials to the inquiry cart and send them together. Pricing, current availability and lot documents are confirmed in that conversation.

Research Use Only. 5-Amino-1MQ is supplied strictly for laboratory research. It is not a drug, supplement or medical product and is not for human or veterinary consumption.

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