Semaglutide Research Peptide
Semaglutide is a 31-amino-acid GLP-1 analogue with a C18 fatty diacid side chain, the standard long-acting reference agonist in GLP-1 receptor research.
6 listed Semaglutide presentations
Each presentation is a separate specification with its own product code. Open one to add it to your inquiry cart or to ask for a quote on WhatsApp. Pricing, availability and lot documents are confirmed for each order.
| Presentation | Per vial | Per box | Product code |
|---|---|---|---|
| Semaglutide 5 mg → | 5 mg | 10 vials | SM5 |
| Semaglutide 10 mg → | 10 mg | 10 vials | SM10 |
| Semaglutide 15 mg → | 15 mg | 10 vials | SM15 |
| Semaglutide 20 mg → | 20 mg | 10 vials | SM20 |
| Semaglutide 30 mg → | 30 mg | 10 vials | SM30 |
| Semaglutide 50 mg → | 50 mg | 10 vials | SM50 |
Amounts are per vial. mg, IU and mL describe different quantities and are not interchangeable. For laboratory research use only.
About Semaglutide
Semaglutide is an analogue of human glucagon-like peptide-1, GLP-1(7-37). Two amino-acid substitutions, α-aminoisobutyric acid (Aib) at position 8 and arginine at position 34, protect it from cleavage by dipeptidyl peptidase-4 (DPP-4) and allow a C18 fatty diacid side chain to be attached through a linker at lysine 26.
The fatty diacid binds albumin reversibly, which is the main reason semaglutide lasts far longer than native GLP-1. It is a selective GLP-1 receptor agonist and is widely used as a reference compound in GLP-1 receptor pharmacology.
Research context
Semaglutide is used to characterize GLP-1 receptor activation, receptor internalization and downstream cAMP signaling, and in preclinical studies of glucose homeostasis, gastric emptying and central appetite circuits.
Because its structure and pharmacology are well documented, it is also the usual comparator for newer GLP-1, dual and triple agonists, and it is one of the two components of the CagriSema combination.
Semaglutide is also the active ingredient of licensed pharmaceutical products in some markets. The material listed here is supplied for laboratory research only; it is not a pharmaceutical product and must not be used as one.
What to confirm for Semaglutide
Check these points with our team before you order:
- The strength per vial; semaglutide is listed in several fills, each with its own product code.
- Whether your protocol calls for semaglutide alone or the cagrilintide and semaglutide blend, which is a separate listing.
- The number of boxes you need and the US delivery destination.
- Which lot documents you require before ordering, such as an identity or purity report.
Semaglutide: frequently asked questions
What makes semaglutide long-acting?
Two modifications: amino-acid substitutions that resist DPP-4 cleavage, and a C18 fatty diacid side chain that binds albumin reversibly and slows clearance.
How does semaglutide differ from liraglutide?
Both are acylated GLP-1 analogues. Liraglutide keeps alanine at position 8 and carries a C16 fatty acid, while semaglutide has Aib at position 8 and a longer C18 fatty diacid with a different linker, which gives stronger albumin binding and a longer half-life.
Which Semaglutide presentations are listed?
6 presentations are listed: 5 mg (SM5), 10 mg (SM10), 15 mg (SM15), 20 mg (SM20), 30 mg (SM30), 50 mg (SM50). Each is packed 10 vials per box, and every presentation has its own specification page and product code.
How do I request a quote for Semaglutide?
Open the presentation you need and use Ask price to message PureForm Biosciences on WhatsApp, or add several materials to the inquiry cart and send them together. Pricing, current availability and lot documents are confirmed in that conversation.
Related research materials
- Tirzepatide →Dual GIP and GLP-1 receptor agonist peptide for incretin research.
- Liraglutide →Acylated GLP-1 receptor agonist with a C16 fatty-acid side chain.
- CagriSema Blend (Cagrilintide + Semaglutide) →An amylin analogue and a GLP-1 analogue combined in one vial.
- Cagrilintide →Long-acting acylated analogue of the pancreatic hormone amylin.
- Retatrutide →Investigational triple agonist of the GIP, GLP-1 and glucagon receptors.
- Dulaglutide →GLP-1 analogue fused to a modified human IgG4 Fc fragment.
Research Use Only. Semaglutide is supplied strictly for laboratory research. It is not a drug, supplement or medical product and is not for human or veterinary consumption.