IGF-1 LR3 Research Peptide
IGF-1 LR3 is an 83-amino-acid IGF-1 analogue with arginine at position 3 and an N-terminal extension that reduce capture by IGF-binding proteins.
2 listed IGF-1 LR3 presentations
Each presentation is a separate specification with its own product code. Open one to add it to your inquiry cart or to ask for a quote on WhatsApp. Pricing, availability and lot documents are confirmed for each order.
| Presentation | Per vial | Per box | Product code |
|---|---|---|---|
| IGF-1 LR3 0.1 mg → | 0.1 mg | 10 vials | IG01 |
| IGF-1 LR3 1 mg → | 1 mg | 10 vials | IG1 |
Amounts are per vial. mg, IU and mL describe different quantities and are not interchangeable. For laboratory research use only.

About IGF-1 LR3
IGF-1 LR3 is a modified form of insulin-like growth factor 1. Glutamic acid at position 3 is replaced by arginine, the “R3”, and a 13-amino-acid extension is added at the N-terminus, the “Long”, giving 83 amino acids instead of 70.
These changes sharply reduce binding to IGF-binding proteins, which normally sequester IGF-1. More of the molecule stays free to activate the IGF-1 receptor, so it is more potent than native IGF-1 in many in vitro systems.
Research context
IGF-1 LR3 is widely used as a cell-culture additive, including in serum-free media for recombinant protein production, and as a tool in research on IGF-1 receptor signaling, the PI3K–Akt and MAPK pathways and cell proliferation.
What to confirm for IGF-1 LR3
Check these points with our team before you order:
- The quantity per vial; IGF-1 LR3 is listed in both sub-milligram and milligram fills.
- The expression system and identity documentation for this recombinant polypeptide.
- The number of boxes you need and the US delivery destination.
- Which lot documents you require before ordering, such as an identity or purity report.
IGF-1 LR3: frequently asked questions
What does LR3 mean?
“Long” refers to the 13-amino-acid N-terminal extension and “R3” to the arginine substituted at position 3. Together they reduce binding to IGF-binding proteins.
How does IGF-1 LR3 differ from IGF-DES?
Both reduce capture by IGF-binding proteins. IGF-DES does it by lacking the first three amino acids, while IGF-1 LR3 substitutes position 3 and adds an N-terminal extension.
Which IGF-1 LR3 presentations are listed?
2 presentations are listed: 0.1 mg (IG01), 1 mg (IG1). Each is packed 10 vials per box, and every presentation has its own specification page and product code.
How do I request a quote for IGF-1 LR3?
Open the presentation you need and use Ask price to message PureForm Biosciences on WhatsApp, or add several materials to the inquiry cart and send them together. Pricing, current availability and lot documents are confirmed in that conversation.
Related research materials
- IGF-DES →des(1-3)IGF-1, a truncated IGF-1 with reduced IGFBP binding.
- MGF (Mechano Growth Factor) →E-domain peptide of the mechano growth factor splice variant of IGF-1.
- PEG-MGF →PEGylated mechano growth factor peptide with extended stability.
- HGH 191AA (Somatropin) →Recombinant 191-amino-acid human growth hormone.
Research Use Only. IGF-1 LR3 is supplied strictly for laboratory research. It is not a drug, supplement or medical product and is not for human or veterinary consumption.